October 2023
Center for Security and Emerging Technology (CSET)
How can policymakers credibly reveal and assess intentions in the field of artificial intelligence? Policymakers can send credible signals of their intent by making pledges or committing to undertaking certain actions for which they will pay a price—political, reputational, or monetary—if they back down or fail to make good on their initial promise or threat. Talk is cheap, but inadvertent escalation is costly to all sides.
June 26, 2023
Georgetown Journal of International Affairs
“The weaponization of the scientific and technological breakthroughs stemming from human genome research presents a serious global security challenge. Gene-editing pioneer and Nobel Laureate Jennifer Doudna often tells a story of a nightmare she once had. A colleague asked her to teach someone how her technology works. She went to meet the student and ‘was shocked to see Adolf Hitler, in the flesh.’
Doudna is not alone in being haunted by the power of science. Famously, having just returned home from Los Alamos in early 1945, John von Neumann awakened in panic. ‘What we are creating now is a monster whose influence is going to change history, provided there is any history left,’ he stammered while straining to speak to his wife. He surmised, however, that ‘it would be impossible not to see it through, not only for military reasons, but it would also be unethical from the point of view of the scientists not to do what they knew is feasible, no matter what terrible consequences it may have.'”
June 23, 2023
PLOS One
“The COVID-19 pandemic is the first to be rapidly and sequentially measured by nation-wide PCR community testing for the presence of the viral RNA at a global scale. We take advantage of the novel “natural experiment” where diverse nations and major subnational regions implemented various policies including social distancing and vaccination at different times with different levels of stringency and adherence. Initially, case numbers expand exponentially with doubling times of ~1–2 weeks. In the nations where interventions were not implemented or perhaps lees effectual, case numbers increased exponentially but then stabilized around 102-to-103 new infections (per km2 built-up area per day).
Dynamics under effective interventions were perturbed and infections decayed to low levels. They rebounded concomitantly with the lifting of social distancing policies or pharmaceutical efficacy decline, converging on a stable equilibrium setpoint. Here we deploy a mathematical model which captures this V-shape behavior, incorporating a direct measure of intervention efficacy. Importantly, it allows the derivation of a maximal estimate for the basic reproductive number Ro (mean 1.6–1.8). We were able to test this approach by comparing the approximated “herd immunity” to the vaccination coverage observed that corresponded to rapid declines in community infections during 2021. The estimates reported here agree with the observed phenomena. Moreover, the decay (0.4–0.5) and rebound rates (0.2–0.3) were similar throughout the pandemic and among all the nations and regions studied. Finally, a longitudinal analysis comparing multiple national and regional results provides insights on the underlying epidemiology of SARS-CoV-2 and intervention efficacy, as well as evidence for the existence of an endemic steady state of COVID-19.”